Structure and mechanism in organic chemistry

Molecular Mechanism of Acrylamide Neurotoxicity: Lessons Learned from Organic Chemistry

BACKGROUND Acrylamide (ACR) produces cumulative neurotoxicity in exposed humans and laboratory animals through a direct inhibitory effect on presynaptic function. OBJECTIVES In this review, we delineate how knowledge of chemistry provided an unprecedented understanding of the ACR neurotoxic mechanism. We also show how application of the hard and soft, acids and bases (HSAB) theory led to the ...

Organic chemistry in water.

Water has emerged as a versatile solvent for organic chemistry in recent years. Water as a solvent is not only inexpensive and environmentally benign, but also gives completely new reactivity. The types of organic reactions in water are broad including pericyclic reactions, reactions of carbanion equivalent, reactions of carbocation equivalent, reactions of radicals and carbenes, transition-met...

Organic and Biomolecular Chemistry

Symmetry in Organic Chemistry

Separation in Organic Chemistry

Separation methods used in organic chemistry are briefly reviewed, emphasis being placed on aspects that are frequently ignored, and special attention being paid to the analytical applications of separation. The relevance of physical, inorganic and analytical chemistry for organic chemistry is stressed. The term 'separation' can be used in analytical chemistry in both a literal and figurative s...